Dolastatin hydrochloride refers to derivatives of dolastatin 10, a highly potent anticancer pentapeptide isolated from marine organisms (sea hares and cyanobacteria) that works by inhibiting microtubule assembly, disrupting cell division (mitosis), and inducing cancer cell death (apoptosis). While dolastatin 10 itself has shown strong anti-cancer activity in labs, its derivatives, like MMAE, are used in modern Antibody-Drug Conjugates (ADCs) such as Adcetris (brentuximab vedotin), to target cancer cells more effectively, reducing systemic toxicity and treating lymphomas and other cancers.

Make: Hetero

Grade: IP

HSimvastatin is a widely prescribed statin medication used to lower "bad" cholesterol (LDL) and triglycerides in the blood, and increase "good" cholesterol (HDL), thereby reducing the risk of heart attack and stroke. The hydrochloride (HCl) form refers to the specific salt formulation of the active drug.

Make: Hetero

Grade: IP / USP